Which of the following is required for Unit-Dose packaging?

Unit-dose packaging is designed to enhance medication safety and efficacy, providing individual doses of a drug that are ready for administration without the need for further preparation. The key characteristic of unit-dose packaging is that each dose is separately and securely packaged to prevent contamination and errors in dosing.

Individually sealed doses ensure that each unit is tamper-proof and maintains its integrity, allowing for accurate dispensing and administration. This is crucial in a healthcare setting where cross-contamination and dosing errors can lead to significant patient harm.

In contrast, reusable containers, delivery on demand, and multi-dose vials do not align with the principles of unit-dose systems. Reusable containers may compromise the integrity of the medication and lead to contamination, while delivery on demand is not a foundational requirement of unit-dose packaging. Multi-dose vials, which contain several doses in one container, clearly do not meet the unit-dose packaging criterion of providing single, individually sealed doses.

Therefore, the requirement for individually sealed doses is fundamental to unit-dose packaging, ensuring that medications are safely and effectively provided to patients.